Clinical observation of plateletes p - selectin expression in acute ischemic cerebrovascular diseases 選擇素表達的臨床觀察
The clinical diagnostic value of detection of p - selectin , il - 1 , sfas , sfasl , am in differentiating tuberculous pleural effusions from malignant pleural effusions 選擇素等多項指標檢測在胸腔積液鑒別中的應用價值
Recently , many adhesion molecules have been used in practice of forensic pathology , intercellular adhesion molecule - 1 ( icam - 1 ) and p - selectin are considered to be closely involve in wound healing . the authors immunohistochemically examined the time - dependent expression of icam - 1 and p - selectin 本研究應用免疫組織化學方法,觀察大鼠皮膚切創后不同時間細胞間粘附分子( icam - 1 )及p選擇素的表達變化,以期確定這兩種物質表達與損傷時間變化的規律,為皮膚損傷時間判定提供有效的免疫組織化學指標。
P - selectin was negative both in the normal skin and in the postmortem damage group . in the wound specimens aged 1h , we detected expression of icam - 1 in the epidermis , a strong positive staining was observed in 3 hours after wound , and continued to 1 days from the skin was injured after incised , weak staining were showed on epiderm of the injury margin after 3 days incised , and disappeared in 5 days . expression of icam - 1 was also detectable in polymorphonuclear cells ( pmns ) in the wound specim - ents aged 3h 本實驗研究證明,皮膚損傷后表皮層icam1表達增高,其表達呈現一定時間規律性,在損傷后lh ,損傷邊緣表皮細胞即呈黃褐色染色,傷后3h組, icam一二在表皮層中呈深黃褐色,并一直持續至傷后id ,傷后3d組icam 1染色轉淡,呈黃褐色染色,在傷后sd及7d組, 1 m一二表達基本恢復至正常狀態。
百科解釋
P-selectin is a protein that in humans is encoded by the SELP gene.