Like calmodulin and troponin c , caltractin contains four potential calcium - binding sites of predicted helix - loop - helix or ef - hand structure . with the development of technology in biology , more and more academicians study questions for discussion by mutating genes in organisms 中心蛋白的結構類似于鈣調蛋白、肌鈣蛋白c的結構,含有四個ef - hand ( helix - loop - helix )結構,即四個鈣結合位點。
Rt - pcr revealed that two basic helix - loop - helix ( bhlh ) genes , mash - 1 and ngn - 1 , were up - regulated during the differentiation stage of wnt - 1 - overexpressing p19 cells . these results suggest that the wnt - 1 gene promotes neuronal differentiation and inhibits gliogenesis during the neural differentiation of p19 cells , and that neural bhlh genes might be involved in this process 我們的實驗結果提示, wnt - 1基因可能參與了p19細胞神經分化過程中的命運決定, wnt - 1基因能促進神經元細胞的分化,而抑制神經膠質細胞的產生;神經bhlh基因可能與p19細胞神經命運決定和神經細胞分化有關。