Robustness analysis of the ifn - induced jak - stat signaling pathway 干擾素誘導的jak - stat信號通路的魯棒性分析
Jak stat signaling paradigmjak stat 信號發送典范
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Here , the issue of robustness analysis of cell jak - stat signal transduction networks is addressed 因此我們有必要研究細胞在不同生理狀況下的變化情況。
12 yamada s , shiono s , joo a , yoshimura a . control mechanism of jak stat signal transduction pathway . febs lett . , 2003 , 534 : 190 - 196 另外我們還模擬了單個信號蛋白的初始濃度的變化對系統輸出的影響,從而可以看出一些關鍵蛋白組分對系統變化的貢獻。
Stat proteins are activated by g - protein coupled receptors , while it has not been reported whether cck receptors , a kind of g - protein coupled receptors , can activate jak / stat pathway Stat蛋白可被g蛋白偶聯受體激活,而cck受體作為一種g蛋白偶聯受體,是否對jak stat通路具有直接激活作用,尚未見報道。
This is investigated upon a mathematical model of ifn - induced jak - stat signaling pathway by applying robustness analysis which is based on a broad range of simultaneous and systematical parameters variation 我們對細胞的jak - stat信號建立了數學模型,同時系統地改變模型中的動力學參數反應速率參數,然后進行大量的數值模擬實驗。
Quarry bay " jak yu chung " in cantonese is another place of colour and excitement and , insiders say , careful study of the signboards and windows will uncover some surprisingly trendy restaurants with cool atmospheres and superb food 魚涌是另一個充滿特色的地方。不少識途老馬都表示,只要小心觀看廣告招牌和櫥窗,定會發現不少令人喜出望外的時尚餐廳,讓您在優雅的氣氛中品嘗各式美食。