Because of the capability of gm1 binding , ctb can enhance vaccine efficacy by inducing mucosal and systemic immune responses . plant bioreactor is a safe and cheap protein production system 由于ctb的載體功能, ctb和cs3融合的形式( ctb cs3 )免疫原性優(yōu)于單獨存在的ctb和cs3單個蛋白,并可達到雙抗霍亂弧菌以及毒素大腸桿菌的目的。
In 1994 , conry firstly constructed cea dna vaccine , studied its immunological effects and made great achievements . in order to enhance dna vaccine efficacy , researchers are inclined to employ effective and safe vectors , co - delivery cytokines recombinant or adhesion molecules , iss , and so on 1994年, conry鄭州大學醫(yī)學院2002研究生畢業(yè)論文癌胚抗原a疫苗構建及佐劑對其兔疫效應的影響就構建了ceadna疫苗,并在動物體內誘導產生了良好的兔疫效果。
百科解釋
Vaccine efficacy is defined as the reduction in the incidence of a disease among people who have received a vaccine compared to the incidence in unvaccinated people. It is usually measured in a randomised controlled trial (RCT) The efficacy of a new vaccine is measured in phase II or phase III clinical trials by giving one group of people a vaccine and comparing the incidence of disease in that group to another group of people who do not receive the vaccine.