As demonstrated in large clinical trials of 2 to 4 years ' duration , these medications significantly increase weight loss compared with placebo ; weight loss with these drugs reaches a nadir between 20 and 28 weeks ; weight loss , averaged 8 % - 10 % , with the placebo contributing 4 % - 6 % of that 為期2 - 4年的大規(guī)模臨床實驗顯示,這些藥物與安慰劑相比可明顯使體重減輕;這些藥物引起的體重減輕在20 - 28周達到最低;可使體重平均降低8 - 10 ,而安慰劑僅為4 - 6 。
In the , sandwichman , distributor of throwaways , nocturnal vagrant , insinuating sycophant , maimed sailor , blind stripling , superannuated bailiff s man , marfeast , lickplate , spoilsport , pickthank , eccentric public laughingstock seated on bench of public park under discarded perforated umbrella . destitution : the inmate of old man s house royal hospital , kilmainham , the inmate of simpson s hospital for reduced but respectable men permanently disabled by gout or want of sight . nadir of misery : the aged impotent disfranchised ratesupported moribund lunatic pauper 行乞方面:欺詐成性的破產者,對每一英磅的欠款只有一先令四便士的微乎其微的償還能力者,廣告人,撒傳單的,夜間的流浪漢,巴結求寵的諂媚者,缺胳膊短腿的水手,雙目失明的青年,為法警跑腿的老朽318 ,宴會乞丐,舔盤子的,專掃人興的,馬屁精,撐著一把撿來的凈是窟窿的傘,坐在公園的長凳上,成為公眾笑料的怪人。