Phenotypic and genotypic characteristics of japanese encephalitis live attenuated vaccine virus sa14 - 14 - 2 and its stability 2弱毒株的表型和基因型特性及其穩定性
A prospective study on the united immunization of live attenuated vaccine and inactivated vaccine against japanese encephalitis 乙腦滅活與減毒活疫苗聯合免疫的前瞻性研究
Study on the strategy of japanese encephalitis immunization using live attenuated vaccine combined with inactivated vaccine 流行性乙型腦炎滅活疫苗與減毒活疫苗相結合的免疫策略研究
Currently , fmd vaccines are either conventionally inactivated vaccines or attenuated vaccines . both types of vaccines are not completely safe and pose some fatality risks 而傳統的滅活疫苗和弱毒疫苗由于其潛在的危險性,使其應用受到很大的限制。
The traditional inactivated or attenuated vaccines could not provide enough protection against these variants and wibdv . therefore , a new generation of more effective and safer vaccines is anticipated . the purpose of this study was to develop a dna vaccine against ibdv 用弱毒苗和滅活苗免疫雞群是目前防治ibd的主要方法,但隨著ibdv變異株與超強毒株的出現,免疫失敗常有發生。
But ib attenuated vaccine has many defects , such as the possibility of contamination of foreign and vertical transmissible pathogens , and the virulent recovery of vaccine virus . therefore , exploring the safe and efficient new vaccines has become the hotspot in the research of ib control 由于活疫苗存在外源性或垂直傳播性病原污染、毒力返祖等缺陷,開發安全、有效的新型疫苗是ib控制的研究重點。
Rates of hospitalization for any cause during the 180 days after vaccination were higher among the recipients of live attenuated vaccine who were 6 to 11 months of age ( 6 . 1 % ) than among the recipients of inactivated vaccine in this age group ( 2 . 6 % , p = 0 . 002 ) 在6 - 11個月年齡組的兒童接受減毒活疫苗后180天內因任何原因導致的住院率的升高幅度( 6 . 1 % )較接受滅活疫苗的同一年齡組的升高率( 2 . 6 % , p = 0 . 002 )為高。
Although the traditional vaccines have played active role in prevention and controlling the disease , many deficiencies exist still such as inactivated vaccine being expensive and inducing strongly response at the injected tissue , as well as the recovery of the attenuated vaccine 傳統疫苗對gpv的預防和控制起到了一定的積極作用,但同時滅活苗存在生產成本高,注射局部炎癥反應較強等弊端,弱毒苗又易發生毒力返強等。
Prevention and cure of the derzsy ' s disease depended on vaccine and antiserum , antibodies of eggs . the vaccines includes goose embryo and duck embryo vaccines which were used 1n breed goose and goslings , and those vaccines have great effect in breeding goose , but the entire virion live vaccines and attenuated vaccines exist many deficiencies . such as preclinical infection , dissemination of virus , recovery of viru5 , etc . those proplems can be sol / ed by producing genetic engineering " asclne 目前使用的疫苗分為種鵝用和雛鵝用的鵝胚和鴨胚化疫苗,這些疫苗在實際生產中發揮巨大作用,因其為全毒苗或弱毒苗,存在著潛伏感染,排毒散毒,毒力返祖的缺陷,基因工程疫苗的研制可解決上述問題。
百科解釋
An attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live"). Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent.